You searched for genetic screens

Inference of drug off-target effects on cellular signaling using Interactome-Based Deep Learning

Nikolaos Meimetis, Douglas A. Lauffenburger, Avlant Nilsson

Selected by Benjamin Dominik Maier

The loss of DNA polymerase epsilon accessory subunits POLE3-POLE4 leads to BRCA1-independent PARP inhibitor sensitivity

Hasan Mamar, Roberta Fajka-Boja, Mónika Mórocz, et al.

Selected by Audrey Noireterre

A transposase-derived gene required for human brain development

Luz Jubierre Zapater, Elias Rodriguez-Fos, Merce Planas-Felix, et al.

Selected by Amanda Ivanoff

High-throughput aminoacyl-tRNA synthetase engineering for genetic code expansion in yeast

Jessica T. Stieglitz, James A. Van Deventer

Selected by Zhang-He Goh

A genome-wide knock-out screen for actors of epigenetic silencing reveals new regulators of germline genes and 2-cell like cell state

Nikhil Gupta, Lounis Yakhou, Julien Richard Albert, et al.

Selected by María Mariner-Faulí

An engineered transcriptional reporter of protein localization identifies regulators of mitochondrial and ER membrane protein trafficking in high-throughput screens

Robert Coukos, David Yao, Mateo I. Sanchez, et al.

Selected by Lorenzo Lafranchi

Hydrophobic-cationic peptides enhance RNA polymerase ribozyme activity by accretion

Peiying Li, Philipp Holliger, Shunsuke Tagami

Selected by Utrecht Protein Folding and Assembly

Transgenerational Regulation of Sexual Attractiveness in C. elegans Nematodes

Itai Antoine Toker, Itamar Lev, Yael Mor, et al.

Selected by Yasmin Lau

Rab34 GTPase mediates ciliary membrane biogenesis in the intracellular ciliogenesis pathway

Anil Kumar Ganga, Margaret C. Kennedy, Mai E. Oguchi, et al.

Selected by Nicola Stevenson

Selective dephosphorylation by PP2A-B55 directs the meiosis I - meiosis II transition in oocytes

S. Zachary Swartz, Hieu T. Nguyen, Brennan C. McEwan, et al.

Selected by Federico Pelisch, Samuel Taylor

Aberrant replication licensing drives Copy Number Gains across species

Patroula Nathanailidou, Michalis Petropoulos, Styliani Maxouri, et al.